British Journal of Cancer Management

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The clinical management of mantle cell lymphoma
BJCM, Volume 2, Number 2.

The management of mantle cell lymphoma (MCL) presents some particular difficulties to the clinician. It is now clear that as a distinct entity within the non-Hodgkin’s lymphomas (NHL), MCL has the worst prognosis of all subtypes, with a five-year survival rate of around 27%.1 While many patients will respond to firstline therapy, this response is rarely complete and a large proportion of patients will relapse within 18 months,2 at which point further treatment is often inadequate.

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