British Journal of Cancer Management

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Adjuvant breast cancer drugs – blockbusters or bankrupters?
BJCM, Volume 2, Number 3.

Since the first trial of adjuvant chemotherapy for early breast cancer,1 there have been over 200 randomised trials demonstrating reduced annual odds of recurrence and death.2 These benefits, to a varying degree, apply regardless of age, stage, nodal status and hormone receptor status.3 More recently, trials have explored strategies to achieve incremental gain by using a variety of newer drugs, dose intensities and sequences with other chemotherapy drugs, surgery, radiotherapy and hormones.

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